OxyContin is an effective analgesic drug. OxyContin without prescription should be primarily bought by patients, who need daily long-term use of strong pain medication for getting rid of acute pain episodes.
OxyContin is a trade mark of Oxycodone. This is a semi-synthetic opioid analgesic, whose analgesic properties are similar to Morphine action. However, the side effects of OxyContin are less pronounced than of Morphine, since it has no effect on the opioid receptors of the central nervous system.
OxyContin is a pure opioid agonist. When administered, this analgesic stimulates certain opioid receptors. Once Oxycodone binds to opioid receptors, it promotes a gradual decrease in the excitability stimuli and pain relief.
OxyContin has a good absorbency. Due to the fact that Oxycodone is a fat-soluble component, fatty and high-calorie food, consumed before the intake of the painkiller OxyContin increases its absorption by approximately 25%.
A single dose of OxyContin provides an analgesic effect for about 12 hours. The half-life may vary from 4 to 4.5 hours after the administration. Stable drug concentrations in the patient’s body are achieved in the second day of OxyContin use.
OxyContin differs from other opioid analgesics by a much broader dosage limits. The online pharmacies offer for sale OxyContin tablets without prescription, containing 5, 10, 15, 20, 30, 40, 60, 80, 120 and 160 mg of Oxycodone.
If the patient is less susceptible to the opioids action, he may enhance the analgesic effect by increasing the dose of OxyContin.
Only a healthcare professional should prescribe OxyContin. When prescribing this opioid analgesic, the doctor should:
- select an individual dosage for each patient;
- take into account the previous experience (if any) of the patient on the use of opioid analgesics;
Patients, for whom OxyContin is the first opioid analgesic, may start using it with the dose of 10 mg twice a day. The daily dose of OxyContin for those patients that combine OxyContin with other opioid analgesics should be calculated, based on the doses of other opiates.
OxyContin should not be the first opioid analgesic for children aged 11 and more. This drug may be used only by children, who have shown tolerance to the 20 mg dose of opioids for at least 5 days.
Each OxyContin tablet should be swallowed in whole with plenty of water. Cutting, breaking or chewing pills may accelerate the release of the active ingredient, which may cause the rapid ingestion of a potentially fatal dose of Oxycodone.
Discontinuation of OxyContin should be gradual. Abrupt cessation of analgesics may lead to the withdrawal syndrome. It may be accompanied by the following symptoms: general weakness, anxiety, nausea, increased heart rate, and others.
Frequent and prolonged “off-label” use of OxyContin may lead to drug dependence. The most common opiate addiction occurs, when the dose of the opioid is increased unreasonably.
OxyContin is not the first Oxycodone-based drug, but it is the first product, in which the pharmaceutical form with a prolonged analgesic effect was used. This analgesic was developed in 1995 by Purdue Pharma. OxyContin was specifically created for reducing the risk of dependence and side effects of opioid analgesics.
Once the clinical trials confirmed the safety and efficacy of OxyContin in the treatment of severe and acute pain, this analgesic has been approved by the FDA. It happened on December 12, 1995, and a year later OxyContin was launched for sale in the USA.
Initially, patients could find OxyContin tablets of 10, 20 and 40 mg. A little later, tablets of 80 mg went on sale, and in 2000 – of 160 mg. OxyContin tablets may be bought without prescription in dozens of different online pharmacies. You have the possibility to order their delivery in almost any country in the world, including: the USA, Sweden, Australia, Canada, Norway, Finland, Ireland, New Zealand, the Netherlands, Denmark, the United Kingdom, South Africa, Switzerland, Belgium, France, Brazil, and Poland.