Buy cheap tizanidine 4mg online

tizanidine

Tizanidine is a centrally acting muscle relaxant. This medicine is used in diseases and pathological conditions, accompanied by painful cramping or muscle tension. Patients, whose physical activity was partially lost as a result of spasticity, should also buy Tizanidine without prescription.

Head injury, stroke or a brain tumor may damage the neural connections of the brain and the spinal cord. This results in spasticity – a pronounced muscle stimulation. Speech and motor activity are completely or partially broken because of spasticity.

Spasticity treatment involves the use of non-drug and drug therapies. Non-drug therapies for spasticity are massages, physical exercises, cryotherapy and others. Tizanidine medication is indicated among the first-line treatment of spasticity.

Tizanidine is a derivative of Imidazole – an organic compound, which is part of many essential amino acids. Tizanidine exerts its therapeutic effect in the spinal cord by stimulating the activity of certain receptors and suppressing the effects of others, at the same time. The muscle relaxant inhibits the transfer of the neural connections in the spinal cord, responsible for the excessive muscle tone.

Tizanidine has an antispasmodic action. That is, the muscle relaxant not only eliminates the increased muscle tone, but also promotes the expansion of blood vessels, as well as the removal of pain symptoms.

Tizanidine is rapidly absorbed after the oral intake, and the maximum plasma concentration is reached in about 60 minutes. The half-life of Tizanidine is about 2-2.5 hours, and the half-life of the active metabolites is 20-40 hours. Fat and high-calorie foods may increase the period of reaching the maximum concentration.

Tizanidine tablets or capsules may be taken after a meal and on an empty stomach. Yet, for example, if a patient took this muscle relaxant for the first time on an empty stomach, then all subsequent Tizanidine intakes should also be done on an empty stomach. These guidelines must be followed to ensure that no changes arise in the muscle relaxant action speed throughout the entire course of treatment with Tizanidine.

The initial Tizanidine dose is 2 mg every 6-8 hours a day. However, no more than three intakes of muscle relaxant are allowed during the day. The single dose of this muscle relaxant may be increased by 2 or 4 mg every 2-4 days, but a single Tizanidine dose should not exceed 16 mg. The total daily dose of Tizanidine should not exceed 36 mg.

When ordering Tizanidine online without prescription, please, note that the effect of this muscle relaxant is dose-dependent. That is, the antispasmodic action enhances with each Tizanidine intake. Qualitative improvement of the patient’s condition occurs on 5-7 day of the muscle relaxant administration. By this time, the degree of spasticity reduces and the motor performance improves.

Do not discontinue the use of this muscle relaxant abruptly. Patients, who received high doses of Tizanidine (20-36 mg daily) for a period of two months or more, must gradually reduce the dose by 2-4 mg per day. Reducing the dosage of muscle relaxant should be carried out in direct proportion to its increase. This is to avoid the withdrawal syndrome.

Advantages of Tizanidine:

  • Tizanidine virtually doesn’t induce the development of muscle weakness
  • in addition to the muscle relaxant action, it also has an analgesic effect;
  • in combined use with the nonsteroidal anti-inflammatory drugs (NSAID), enhances their effect;
  • effectively eliminates sudden muscle spasms and increased muscle tone in chronic spasticity.

By purchasing Tizanidine without prescription, the patient may get another advantage from the use of this muscle relaxant. Tizanidine does not irritate the gastric mucosa and does not cause any adverse reactions from the gastrointestinal tract.

The gastroprotective properties of Tizanidine are particularly important in the combined therapy of this muscle relaxant with the NSAID, the main side effects of which are exactly the digestion problems.

Tizanidine has been used since 1996 in most countries of the world. In the USA, the first Tizanidine Hydrochloride containing drug was registered on the 5th of November, 1996, and almost a year later the muscle relaxant appeared on the market under the non-proprietary name.

On September 6, 2002, the pharmaceutical company Elan received the FDA approval for the production of capsules containing 2, 4 and 6 mg of Tizanidine under the brand name Zanaflex. However, on July 28, 2004, Elan sold all its rights for Zanaflex to another company, Acorda. Since then, all rights to the sale and marketing of Tizanidine-containing products belong to the pharmaceutical company Acorda.

Before buying Tizanidine online without prescription, patients may find all necessary information about this muscle relaxant on various Internet resources. For example, the official website of the nonprofit educational organization Erowid has many reviews on Tizanidine, in which users share their experience for this muscle relaxant.